Two mefenamic acid derivatives: structural characterization from PXRD and MEP
نویسندگان
چکیده
منابع مشابه
Study of Anthranylic Acid Derivatives: Mefenamic Acid and Its Various Analogues
Anthranylic acid derivatives are direct structural analogs of salicylic acid derivatives. They possess analgesic, anti-inflammatory, and antipyretic activity. They are similar to pyrazolones in terms of analgesic and antipyretic activity, yet they exceed the anti-inflammatory activity of salicylates. The mechanism of action of this series of nonsteroid, anti-inflammatory analgesics is not concl...
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The clinical, radiological, and histological features of two patients with severe intestinal damage induced by mefenamic acid and mimicking coeliac disease are described. Symptoms rapidly reverted on withdrawal of the drug, and in one case, did not relapse during treatment with other non-steroidal anti-inflammatory drugs.
متن کاملPurification and Characterization of Two Acid Phosphatases from Germinating Peanut (Arachis hypogaea) Seed
The maximum acid phosphatasic activity was detected in peanut seed at the 5th day of germination. At least, two acid phosphatases were purified by successive chromatography separations on DEAE-Sepharose CL-6B, CM-Sepharose CL-6B, Sephacryl S-100 HR, and Phenyl-Sepharose HP to apparent homogeneity from five days old cotyledon of peanut after germination. These isoenzymes, designated peanut cotyl...
متن کاملSynthesis and anti-inflammatory evaluation of novel piperazine derivatives of mefenamic acid
In order to explore novel anti-inflammatory agents, some novel mefenamic acid derivatives as potential non-steroidal antiinflammatory agents (NSAIDs) were synthesized and characterized by IR, H-NMR, C-NMR, mass and elemental analysis. The anti-inflammatory activities of the target compounds were evaluated via the croton oil-induced ear oedema test in mice. According to screened results, compoun...
متن کاملMefenamic acid-induced bullous pemphigoid.
A 52 year old man developed bullous pemphigoid, Coombs' positive haemolytic anaemia and diarrhoea related to the use of mefenamic acid. Clinical manifestation of the bullous pemphigoid, haemolytic anaemia and diarrhoea resolved following discontinuation of the mefenamic acid. Mefenamic acid should be added to the list of agents that are known to induce bullous pemphigoid.
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations and Advances
سال: 2017
ISSN: 2053-2733
DOI: 10.1107/s2053273317086272